RD-11.15-16.2022-Wang

Conference Video|Duration: 30:35
November 16, 2022
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    International Association for the Study of Pain (IASP) defines “pain” as “an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage”. The emotions elicited by pain are strongly coupled with autonomic responses that often feeds back to further enhance pain perception. Indeed, the sensory pathways that detect and transmit painful stimuli (i.e the nociceptive system) functionally intersect with the autonomic system at multiple subcortical and spinal levels. Nociceptive stimuli can directly evoke activity of the sympathetic system through spinal circuits, inducing changes in blood pressure and local blood flow before the occurrence of conscious perception of pain. Persistent sympathetic activation can increase electromyographic activity in back and neck muscles thereby generating painful spasms. On the other hand, attention, anticipation, cognitive appraisal can either elevate or dampen the autonomic responses to noxious stimulation through top-down controls. Many brain regions involved in pain perception, such as the anterior cingulate cortex (ACC), the insular cortex, amygdala, and periaqueductal gray (PAG), also regulate autonomic system activity. There is growing interest in mindfulness-based method to treat chronic pain. It has been suggested that mindfulness interventions relieve pain in part through modulating the balance of the autonomic system activities.
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  • Video details
    International Association for the Study of Pain (IASP) defines “pain” as “an unpleasant sensory and emotional experience associated with, or resembling that associated with, actual or potential tissue damage”. The emotions elicited by pain are strongly coupled with autonomic responses that often feeds back to further enhance pain perception. Indeed, the sensory pathways that detect and transmit painful stimuli (i.e the nociceptive system) functionally intersect with the autonomic system at multiple subcortical and spinal levels. Nociceptive stimuli can directly evoke activity of the sympathetic system through spinal circuits, inducing changes in blood pressure and local blood flow before the occurrence of conscious perception of pain. Persistent sympathetic activation can increase electromyographic activity in back and neck muscles thereby generating painful spasms. On the other hand, attention, anticipation, cognitive appraisal can either elevate or dampen the autonomic responses to noxious stimulation through top-down controls. Many brain regions involved in pain perception, such as the anterior cingulate cortex (ACC), the insular cortex, amygdala, and periaqueductal gray (PAG), also regulate autonomic system activity. There is growing interest in mindfulness-based method to treat chronic pain. It has been suggested that mindfulness interventions relieve pain in part through modulating the balance of the autonomic system activities.
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