Prof. J Christopher Love

The Love Lab is exploring the heterogeneity present in populations of cells and characterizing the dynamic biological responses of individual cells subjected to defined perturbations. We develop new processes for analyzing large numbers of individual living cells quantitatively and dynamically. The primary approach uses simple technologies, based on soft lithography or unconventional nanofabrication, to measure multiple characteristics of single cells, and from those data, we aim to construct detailed profiles that describe the state and evolution of the cell itself or the multicellular population of which it is a member.

The long-term objectives of the Lab's work is to understand how heterogeneity in populations of cells affects their collective behaviors as a system, and to gain insights into the biological variations present in unique and rare cells from those populations. Another aim is to facilitate the transfer of these technologies into clinical laboratories for extended use in biomedical research.