Skip to main content
MIT Corporate Relations
MIT Corporate Relations
Search
×
Read
Watch
Attend
About
Connect
MIT Startup Exchange
Search
Sign-In
Register
Search
×
MIT ILP Home
Read
Faculty Features
Research
News
Watch
Attend
Conferences
Webinars
Learning Opportunities
About
Membership
Staff
For Faculty
Connect
Faculty/Researchers
Program Directors
MIT Startup Exchange
User Menu and Search
Search
Sign-In
Register
MIT ILP Home
Toggle menu
Search
Sign-in
Register
Read
Faculty Features
Research
News
Watch
Attend
Conferences
Webinars
Learning Opportunities
About
Membership
Staff
For Faculty
Connect
Faculty/Researchers
Program Directors
MIT Startup Exchange
Back to Faculty/Researchers
Prof. Elizabeth Marie Nolan
Ivan R Cottrell Professor of Immunology
Associate Member, Broad Institute
Primary DLC
Department of Chemistry
MIT Room:
16-573B
(617) 452-2495
lnolan@mit.edu
https://chemistry.mit.edu/profile/elizabeth-marie-nolan/
Assistant
Joanne Baldini
(617) 253-7372
jbaldini@mit.edu
Areas of Interest and Expertise
Metalloproteins and Peptides
Metal Ion Physiology
Host/Pathogen Interactions
Microbial Pathogenesis
Biochemistry
Inorganic and Organic Chemistry
Enzymology
Cell Biology
Research Summary
Professor Nolan’s current research program is motivated by the global problems of infectious disease and antibiotic resistance. We investigate the chemistry and biology of small molecules, peptides, and proteins that participate in the human innate immune response and host/pathogen interaction, and contribute to microbial pathogenesis. In many projects, we emphasize how transition metals, and metal-ion chelators produced by either the host or microbe, contribute to these phenomena. Our experimental approach combines the techniques of inorganic and organic chemistries, biological chemistry, and microbiology.ard Medical School and then returned to MIT as an assistant professor in 2009.
Recent Work
Projects
October 25, 2018
Department of Chemistry
Evaluation of a Reducible Disulfide Linker for Siderophore-mediated Delivery of Antibiotics
Principal Investigator
Elizabeth Nolan
October 25, 2018
Department of Chemistry
Esterase-Catalyzed Siderophore Hydrolysis Activates an Enterobactin–Ciprofloxacin Conjugate and Confers Targeted Antibacterial Activity
Principal Investigator
Elizabeth Nolan
September 17, 2013
Department of Chemistry
Nolan Research Group
Principal Investigator
Elizabeth Nolan
July 18, 2011
Department of Chemistry
S100 Proteins and Zinc in Epidermal Repair
Principal Investigator
Elizabeth Nolan
Related Faculty
Prof. Rick L Danheiser
Arthur C Cope Professor of Chemistry
Prof. Alison Wendlandt
Associate Professor of Chemistry
Prof. Mohammad Movassaghi
Professor of Chemistry