Prof. Elizabeth Marie Nolan

Ivan R Cottrell Professor of Immunology
Associate Member, Broad Institute

Primary DLC

Department of Chemistry

MIT Room: 16-573B

Assistant

Joanne Baldini
jbaldini@mit.edu

Areas of Interest and Expertise

Metalloproteins and Peptides
Metal Ion Physiology
Host/Pathogen Interactions
Microbial Pathogenesis
Biochemistry
Inorganic and Organic Chemistry
Enzymology
Cell Biology

Research Summary

Professor Nolan’s current research program is motivated by the global problems of infectious disease and antibiotic resistance. We investigate the chemistry and biology of small molecules, peptides, and proteins that participate in the human innate immune response and host/pathogen interaction, and contribute to microbial pathogenesis. In many projects, we emphasize how transition metals, and metal-ion chelators produced by either the host or microbe, contribute to these phenomena. Our experimental approach combines the techniques of inorganic and organic chemistries, biological chemistry, and microbiology.ard Medical School and then returned to MIT as an assistant professor in 2009.

Recent Work