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Prof. Ram Sasisekharan

Alfred H Caspary Professor of Biological Engineering and Health Sciences and Technology

Primary DLC

School of Engineering

MIT Room: 76-461C
(617) 258-9494
https://be.mit.edu/faculty/ram-sasisekharan/

Areas of Interest and Expertise

Structure, Kinetics and Transport of Cytokines in Extracellular Matrix
Growth Factors
Extracellular Matrix and Signal Transduction
Macro-Molecular Interactions and Associations at the Cell Surface
Extracellular Environment in Order to Understand How the Extracellular Matrix Regulates Cell Function
Research Geared Towards Eradication of Certain Diseases (Including Some Forms of Cancer)
Molecular Engineering
Therapeutics Development and Delivery
Computational Biology
Biomolecular Engineering
Molecular Pharmacology
Cell and Tissue Engineering
Computational Modeling of Biological and Physiological Systems
Avian Flu Research
Glycomics and Glycobiology
Swine Flu
Nanotechnology
Bioinformatics

Research Summary

Developing computational, structural, analytical and biological tools to decode the structure-function relationships of complex glycans and their interactions with proteins.

The Sasisekharan Laboratory employs multidisciplinary strategies to develop and integrate technologies to further study complex polysaccharides important to a host of disease processes. A central goal is to ultimately develop novel therapeutic approaches to alleviate suffering from disease and promote overall human health. The Sasisekharan Lab has put forth efforts in building and applying various glycomics technologies.

Technologies developed in the Sasisekharan Lab have resulted in the founding of multiple local biotechnology companies.

Recent Work

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