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Prof. H Robert Horvitz
David H Koch Professor of Biology
Member, McGovern Institute
Howard Hughes Medical Institute (HHMI) Investigator
Primary DLC
Department of Biology
MIT Room:
68-425A
(617) 253-4671
horvitz@mit.edu
https://mcgovern.mit.edu/profile/h-robert-horvitz/
Areas of Interest and Expertise
Stem Cells
Cancer
Genetics
Molecular, Developmental, and Behavioral Genetics of the Soil Nematode Caenorhabditis elegans
Cell Lineage, Cell Signaling, Cell Migration, and Cell Death in Nematode Development
Neurodegeneration in the Nematode Caenorhabditis elegans and in Human Disease
Neurobiology
Molecular Medicine and Human Disease
Biological Oceanography
Developmental Biology
Cellular and Genetic Neuroscience
Research Summary
Professor Horvitz studies molecular, developmental and behavioral genetics of the nematode Caenorhabditis elegans and the use of genetics, molecular biology, cell biology, biochemistry and electrophysiology to analyze C. elegans development and behavior. Research also includes human molecular genetics, with a focus on the neurodegenerative disease amyotrophic lateral sclerosis.
Recent Work
Projects
December 29, 2011
Department of Biology
Genetic Analysis of Nematode Egg Laying and Co-Regulated Bahavioral Systems
Principal Investigator
H Horvitz
April 27, 2010
Department of Biology
Neurodegeneration Diseases and Brain Injury Research
Principal Investigator
H Horvitz
September 25, 2008
Department of Biology
How Does the Genome Control Animal Development and Behavior?
Principal Investigator
H Horvitz
April 7, 2008
Department of Biology
A Simple Nervous System
Principal Investigator
H Horvitz
December 21, 2006
Department of Biology
Micro RNAs
Principal Investigator
H Horvitz
March 11, 2003
Department of Biology
C. elegans Neural Development and Behavior
Principal Investigator
H Horvitz
July 13, 1999
Department of Biology
Programmed Cell Death (Apoptosis)
Principal Investigator
H Horvitz
July 13, 1999
Department of Biology
Human Neurologic Disease
Principal Investigator
H Horvitz
April 24, 1999
Department of Biology
Signal Transduction, Transcriptional Repression and Chromatin Remodeling
Principal Investigator
H Horvitz
April 21, 1999
Department of Biology
Morphogenesis
Principal Investigator
H Horvitz
April 20, 1999
Department of Biology
Neural Development and Behavior
Principal Investigator
H Horvitz
April 11, 1999
Department of Biology
Cell Lineage, Cell Fate and MicroRNAs
Principal Investigator
H Horvitz
Related Faculty
Prof. Richard O Hynes
Virginia and Daniel K Ludwig Professor for Cancer Research
Prof. Rudolf Jaenisch
Professor of Biology
Dr. Christian Rueckert
Research Affiliate