The MIT Integrated Learning Initiative (MITili) is a cross-disciplinary, Institute wide initiative to foster quantitative and rigorous research about how people learn and how knowledge from that research can enhance learning from school through adult professional education. MITili aims to integrate knowledge from psychology, economics, neuroscience, engineering, and public policy in pursuit of these goals. The work of the future will require life-long learning, and knowledge from learning science ought to enhance that learning. I will show how knowledge from learning science can enhance work-place learning. I will also review how technology might enable, and in some cases disable, learning. I will also share recent findings about how sleep matters for higher education. Finally, I will share some evidence about the brain bases of adult learning.