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Prof. Jeffrey M Karp

HST Affiliated Faculty
Associate Professor of Medicine and Health Sciences and Technology, Harvard Medical School (HMS) / Brigham & Women's Hospital (BWH)
Co-Director, Regenerative Therapeutics, Brigham and Women's Hospital (BWH)
Principal Investigator, Harvard Stem Cell Institute

Primary DLC

Harvard-MIT Program in Health Sciences and Technology

MIT Room: 76-661
(617) 817-9174
http://www.karplab.net/

Areas of Interest and Expertise

Drug Delivery
Cell Therapy
Needles
Implantable Biomaterials
Medical Adhesives
Medical Devices
CTC Capture Chips
Diagnostic Devices
Biomaterials
BioMEMS
Extracellular Matrix
Therapeutic Technologies
Tissue Engineering
Adult Stem Cells
Synthetic, Self-Assembled and Biodegradable Materials
Future of Healthcare

Research Summary

The Karp lab aims to create advanced biomaterials and devices for therapeutics, taking a highly multidisciplinary approach.

Technologies developed in the Karp lab include high-tech skincare, tissue adhesives, and 3D printed biomedical devices, immunomodulation with biologically responsive materials, small-molecule regenerative therapeutics with an initial target of hearing loss, cannabinoid therapeutics, biomedical devices to improve child safety, needles that automatically stop when they reach their target, and a bioengineered luminal coating for controlled GI targeting.

Recent Work

  • Video

    9.23.20 Approaches in Cell Therapy and Regenerative Medicine

    September 23, 2020Conference Video Duration: 60:34
    In the last decade, the science of cell therapy and regenerative medicine has made remarkable progress. Work in this area has also resulted in numerous engineering successes, enabling sophisticated tools that open the door to new approaches for discovery and development of therapeutics. Particularly noteworthy is the recent progress in cell and molecular biology, including in stem cell research and gene editing. In this webinar, we will hear about new tools and the new directions they make possible as well as how each is being commercialized.

    How can small molecules be identified that evoke cell or tissue regeneration by design? How can we engineer cells and tissue-growth in situ with a structure suitable for implantation? How can we physically gain access to the interior of cells for both discovery and engineering purposes? And how can the immune system be mapped with single-cell biology to accelerate discovery?

Related Faculty

Dr. Berkin Bilgic

HST Affiliated Faculty

Dr. Georges N El Fakhri

HST Affiliated Faculty

Dr. Trishan Panch

Lecturer