Entry Date:
May 3, 2004

Trout Research Group: Molecular Engineering Laboratory

Principal Investigator Bernhardt Trout


The Molecular Engineering Laboratory at MITdevelops and applies sophisticated computational, theoretical, and experimental methods in order to probe complex chemical systems on the molecular level and engineer them for high value chemical applications with maximum specificity. Applications are currently in the fields of continuous pharmaceutical manufacturing, stabilization and formulation of biopharmaceuticals, and nucleation and crystallization. In parallel, we develop new computational methods which are generally applicable for the engineering of complex chemical systems.

Research areas include:

(*) Continuous Pharmaceutical Manufacturing
(*) Stabilization and Formulation of Biopharmaceuticals
(*) Nucleation and Crystallization
(*) Molecular Computational Methods for Reactive Processes in Complex Systems

Professor Trout also directs two major projects focusing on pharmaceuticals. The Novartis-MIT Center for Continuous Manufacturing is a bold new initiative to transform pharmaceutical manufacturing. The Singapore-MIT Alliance Chemical and Pharmaceutical Engineering is an exciting educational and research initiative which give students the opportunity to study both at MIT and in Singapore and perform cutting-edge research in a variety of areas.

Most of the research is industrially funded, and the aim is towards new technology development. Current and past partners, include, Amgen, DuPont, EniTecnologie, Ford Motor Company, Merck & Company, Inc., Novartis, and others. Governmental sponsors include the NSF, NIH, DOE, and the Government of Singapore.

Prof. Bernhardt L. Trout also consults for major pharmaceutical, biotechnology, and chemical companies.

Contact our Principal Investigator, Professor Trout, at: trout@mit.edu