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Prof. Chris Kaiser

Amgen Professor of Biology

Primary DLC

Department of Biology

MIT Room: 68-333B
(617) 253-9804

Areas of Interest and Expertise

Molecular and Cellular Biology of Membrane Transport in the Yeast Saccharomyces cerevisiae
Control of Intracellular Membrane Function Analyzed at the Molecular Level
Structure and Function of Transport Proteins Driving the Formation and Fusion of Transport Vesicles in the Exocytic Pathway in Yeast
Tranport Protein Function Analyzed by Combined Genetic, Cell Biochemical and Immuno-Microscopy Techniques
New Transport Functions Identified by Genetic Screens
Genetics
Cell Biology

Research Summary

The Kaiser Lab studies fundamental mechanisms of protein folding and intracellular trafficking using the yeast S. cerevisiae as a model organism. Our work focuses on the folding of proteins in the endoplasmic reticulum (ER), quality control mechanisms in the ER, and membrane protein sorting in Golgi compartments. We use combined genetic, biochemical and cell biological methods to gain an understanding of the molecular mechanisms that underlie each of these processes.

Recent Work

Related Faculty

Prof. Sara Prescott

Assistant Professor of Biology

Dr. Charley Swofford

Research Scientist

Dr. T G Sambandan

Research Affiliate