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Prof. Domitilla Del Vecchio

Grover M Hermann Professor in Health Sciences and Technology
Professor in Mechanical Engineering
Faculty Lead, MIT Postdoctoral Fellowship Program for Engineering Excellence

Primary DLC

Department of Mechanical Engineering

MIT Room: 3-469B
(617) 452-2275
https://meche.mit.edu/people/faculty/ddv@MIT.EDU

Assistant

Joe Gaken
(617) 324-6108
jgaken@mit.edu

Areas of Interest and Expertise

Control and Dynamical Systems Theory
Systems and Synthetic Biology

Research Summary

Professor Del Vecchio's group focuses on model-based analysis, design, and control of biomolecular networks in living cells. The objective is to make the engineering of synthetic genetic circuits in living organisms more robust to context, modular, and hence more scalable. One of the target applications is the design of synthetic genetic circuits that control cell fate to produce patient-specific somatic cells for regenerative medicine. The approach is grounded on rigorous mathematical analysis of physics-based models of biological network dynamics, on control-theoretic tools for design, and on theory-educated experiments in living cells, from bacterial to mammalian.

Recent Work

Related Faculty

Mr. John Christopher Bachman

Graduate Student

Dr. Jay Senkevich

Research Affiliate

Prof. Henrik Schmidt

Professor of Mechanical and Ocean Engineering