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Prof. Li-Huei Tsai

Picower Professor of Neuroscience

Director, Picower Institute for Learning and Memory
Senior Associate Member, Broad Institute

Primary DLC

Picower Institute for Learning and Memory

MIT Room: 46-4235A

(617) 324-1660

lhtsai@mit.edu

https://picower.mit.edu/faculty/li-huei-tsai

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Areas of Interest and Expertise

Neuroscience
Brain Development and Aging
Alzheimer's Disease
Cdk5

Research Summary

The primary goal is to elucidate the pathological mechanisms underlying neurological disorders affecting learning & memory. The major research areas include neuropsychiatric disorders, autism, and Alzheimer’s disease. Dr. Li-Huei Tsai pursues two avenues of research that run to opposite ends of the human life span – from the brain as it develops in utero, to the brain as it decays in old age. Seemingly separate, they are linked by profound brain mechanisms that govern proper growth as well as proper function.

Projects

January 1, 2021

Picower Institute for Learning and Memory

Aging Brain Initiative (ABI)

Principal Investigators Li-Huei Tsai , Edward Boyden , Emery Brown

January 26, 2016

Picower Institute for Learning and Memory

Tsai Laboratory

Principal Investigator Li-Huei Tsai

January 26, 2016

Picower Institute for Learning and Memory

Modeling Neurological Disorders Using Induced Pluripotent Stem Cells (iPSCs) and Tissue Bioengineering

Principal Investigator Li-Huei Tsai

August 4, 2014

Picower Institute for Learning and Memory

Neuronal Networks, Optogenetics, and Neurodegeneration

Principal Investigator Li-Huei Tsai

August 4, 2014

Picower Institute for Learning and Memory

The Role of Cdk5 in Neurodegeneration and Normal Brain Function

Principal Investigator Li-Huei Tsai

January 9, 2012

Picower Institute for Learning and Memory

The Cdk5/p35 Kinase

Principal Investigator Li-Huei Tsai

January 9, 2012

Picower Institute for Learning and Memory

The Epigenetics of Alzheimer's Disease

Principal Investigator Li-Huei Tsai

October 11, 2011

Picower Institute for Learning and Memory

Chromatin Remodeling and Learning and Memory

Principal Investigator Li-Huei Tsai

December 28, 2006

Picower Institute for Learning and Memory

Neuropsychiatric Disorders

Principal Investigator Li-Huei Tsai

Video

A New Wave of Treatment for Alzheimer's

September 28, 2023MIT Faculty Feature Duration: 21:30

Li-Huei Tsai
Picower Professor of Neuroscience, Director of the Picower Institute for Learning and Memory at MIT

Prof. Li-Huei Tsai

Primary DLC

Areas of Interest and Expertise

Research Summary

Recent Work

Aging Brain Initiative (ABI)

Tsai Laboratory

Modeling Neurological Disorders Using Induced Pluripotent Stem Cells (iPSCs) and Tissue Bioengineering

Neuronal Networks, Optogenetics, and Neurodegeneration

The Role of Cdk5 in Neurodegeneration and Normal Brain Function

The Cdk5/p35 Kinase

The Epigenetics of Alzheimer's Disease

Chromatin Remodeling and Learning and Memory

Neuropsychiatric Disorders

A New Wave of Treatment for Alzheimer's

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