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Solid-state electronic devices and biological systems exhibit drastically disparate materials properties. While semiconductor devices are often hard, brittle, and bound to flat wafers, biological electronics, such as our nervous system, are soft, mobile, and three-dimensional. Our group bridges this material divide between synthetic and biological electronics by creating multifunctional fibers capable of minimally-invasive interfacing with the organs while integrating advanced sensing and stimulation capabilities. This talk will highlight the development and applications of multifunctional fibers to recording and modulation of neural activity in the brain and in the gastrointestinal tract in behaving subjects. Finally, it will demonstrate how bioelectronic devices can be applied to uncover neural circuits underlying gut-brain communication, paving the way to future gut-centric therapies for neurological and psychiatric disorders.
Principal Investigator Yuriy Román
James DiCarlo Director, MIT Quest Peter de Florez Professor of Neuroscience Head, Brain and Cognitive Sciences
Bilge Yildiz Professor, Nuclear Science and Engineering Professor, Materials Science and Engineering
Michael Schrage Research Fellow, MIT Initiative on the Digital Economy, MIT Sloan School of Management Elisabeth B. Reynolds Former Special Assistant to the President for Manufacturing and Economic Development Former Executive Director, MIT Task Force on the Work of the Future Principal Research Scientist Lecturer, Department of Urban Studies and Planning, MIT Department of Urban Studies and Planning Suzanne Berger John M. Deutch Institute Professor of Political Science, MIT Political Science Simon Johnson Ronald A Kurtz (1954) Professor of Entrepreneurship, Professor of Global Economics and Management, MIT Sloan School of Management