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AI and machine learning are becoming embedded in our wearables and smartphones, enabling new insights and interventions for improving lives for patients with conditions including autism, epilepsy, and depression. The latter is growing and forecast to become the #1 disease burden by 2030. How close are we to forecasting changes in mood, stress, and physical health before they happen? Could AI help us prevent future diseases such as depression, and help people stay healthy instead of becoming sick tomorrow? This talk will show the latest findings that suggest that a better mental health future could be possible with AI.