Engineering principles and biological insights can open up new capabilities for biotechnology. This talk will highlight two solutions to challenges faced in improving patient care. First, applying basic principles in chemical engineering to the limitations in blood-based cancer diagnostics today led to new approaches to enhance the amounts of cell-free DNA recovered using a novel 'enhancing agent' similar to contrast agents used in other diagnostics. Second, leveraging biological insights to recast the engineering operations required to enable small biomanufacturing systems for distributed and lower capital-intensive production.
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