Dr. Sean A Clarke

Principal Lecturer

Primary DLC

Department of Biological Engineering

MIT Room: 56-211

Areas of Interest and Expertise

Food Safety Assay Development
Cheese Microbiology
Microbial Ecology and Evolution
Prophage Dynamics and Distribution
Design Methodology

Research Summary

Sean Clarke first joined Biological Engineering (BE) as a Ph.D. student in 2005. After completing his thesis and a postdoc, he worked on applied microbial challenges in two contexts: at the Cellars at Jasper Hill, an award-winning Vermont cheesemaker, and at Sample6, a startup using synthetic biology to solve food safety challenges.

Wanting to contribute to the innovative and inspiring BE community, Clarke returned in 2016 to a dual position. Half of his work is as a communication instructor for the undergraduate communication-intensive lab and capstone courses. In conjunction, he has a new industry liaison role working to improve connections between BE and the thriving local biotech ecosystem.

The outreach role involves addressing the question: “What does a biological engineer do?” The answers come mainly from the stories of our MIT BE S.B. and Ph.D. graduates, who have distinguished themselves in a variety of remarkable careers in the short history of the department. Clarke’s role involves promoting the unique abilities of BE students to the world, and at the same time, sharing with students the knowledge and practices that will help them succeed in their careers at workplaces of all scales, whether in biotech, pharma, non-profit, or other sectors.

Communication skills and collegiality are critical to that success, so Clarke’s role in BE’s teaching faculty connects naturally. In collaboration with other instructors and the BE Communication Lab, he teaches students field-tested practices of clear and effective writing, speaking, and visual design in 20.109 (Lab Fundamentals in Biological Engineering) and 20.380 (Biological Engineering Design).

Recent Work