Entry Date:
January 27, 2023

Tadesse Lab: Rapid Label-Free Cell Fingerprinting

Principal Investigator Loza Tadesse

Project Start Date January 2023


Rapid, accurate disease diagnosis, and real-time monitoring is essential for effective treatments, halting the rise of drug resistance, and achieving personalized health and precision medicine goals. The Tadesse Lab develops next generation point-of-care diagnostic and cell monitoring devices using optical, spectroscopy and nanoscience-based tools with machine learning based data analysis for application in extreme environments including developing nations, extraterrestrial exploration, and military sites. In addition, our tools can be broadly applied in sites where detection and label free fingerprinting of cells is needed such as, quality control in cell therapy manufacturing, food, and water processing. Research program integrates sensing technologies, artificial intelligence tools and needs-based design thinking for translation of tools to targeted clinical and research settings. The Tadesse lab is part of the Department of Mechanical Engineering at MIT and the Ragon Institute of MGH, MIT and Harvard. The lab actively seeking industry collaborations in areas of novel disease diagnostics development and label free cell identification and fingerprinting for applications in cell therapy manufacturing, water and food quality control.