Prof. James G Fujimoto

The Fujimoto group's research focuses on the refinement and application of optical coherence tomography (OCT), a new method of high-resolution imaging developed by Professor Fujimoto and company in 1991. It measures echo time delay and the magnitude of backscattered light in much the same way that an ultrasound B-scan does with sound waves. Recent developments in femtosecond lasers are allowing greater resolution in OCT imaging, which will allow subcellular imaging and improved diagnosis of eye diseases. OCT systems have been demonstrated for advanced arterial imaging, early neoplasia detection, early glaucoma diagnosis and other ophthalmic applications, and for guiding laser surgery. Furthermore, a portable OCT system has been shown effective for real-time high-resolution imaging in a clinical setting. Non-medical uses for OCT imaging include nondestructive evaluation testing of parts and materials in manufacturing and design.