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Prof. Donald E Ingber

Judah Folkman Professor of Vascular Biology
Judah Folkman Professor of Vascular Biology, Surgery, Boston Children's Hospital and Harvard Medical School (HMS)
Professor of Bioengineering, Harvard School of Engineering & Applied Science
Director, Wyss Institute
MIT Room: HARVARD-3 BLAC
(617) 355-8031
http://hst.mit.edu/faculty-research/faculty/ingber-donald

Assistant

Jeanne Nisbet
jeanne.nisbet@childrens.harvard.edu

Areas of Interest and Expertise

Mechanical Stress
Cytoskeleton
Cellular Mechanotransduction
Extracellular Matrix
Focal Adhesions
Experimental Mammary Neoplasms
Mesenteric Vascular Occlusion
Tensile Strength

Research Summary

Donald Ingber is interested in how cell structure and mechanics impact cellular biochemistry and tissue development.?? His research approach has combined techniques from various fields, including molecular cell biology, engineering, chemistry, physics, and computer science.

Ingber's angiogenesis research focuses on how the shape of a vascular blood vessel cell and the physical properties of its environment influence whether the cell grows, produces specialized products, moves, or dies. Through these efforts, Ingber has made pioneering contributions to the fields of angiogenesis, tissue engineering, mechanobiology, and systems biology. His work on how blood vessels form also led to the development of TNP-470, one of the first angiogenesis inhibitors to enter clinical trials.

Recent Work