Entry Date:
September 22, 2016

Neuromodulatory Control of Circuit-Wide Neuronal Dynamics

Principal Investigator Steven Flavell


What circuit-wide patterns of neural activity define distinct behavioral states? We aim to understand how neuromodulators, like serotonin, coordinate neural activity throughout circuits to generate stable behavioral states.

Techniques employed include:
(*) Circuit-wide calcium imaging in freely-moving animals,
(*) Optogenetics,
(*) Mutant analysis,
(*) Quantitative behavioral analysis.