Project Website http://lbrc.mit.edu/research/collaborative-projects/fluorescence-spectroscopy-i…
Ongoing projects in this sector include:
(*) Monitoring neuronal plasticity and synaptic connectivity in vivo(*) Biophotonics studies of liver fibrosis and liver cancer(*) High-throughput depth-selective photodynamic therapy [ PDF ](*) Super-resolution mapping of the connectome in a whole mouse brain(*) Monitoring all 105 synaptic inputs/outputs of an interneuron(*) Continuous glucose monitoring based on fluorescent cellular sensors(*) Studying the molecular pathway underlying peripheral nerve regeneration(*) Evaluating pheomelanin as a carcinogenic agent(*) Fluorescence energy transfer based heme sensor for malaria studies(*) Normalization of tumour blood vessels for improved the delivery of nanomedicines(*) Decompressing tumour blood vessels to enhance drug delivery and potentiate chemotherapy(*) Nanoparticle size series for in vivo fluorescence imaging(*) Fluorescent nanorods and nanospheres for real-time in vivo probing of nanoparticle shape-dependent tumor penetration(*) Multistage nanoparticles for improved delivery into tumor tissue(*) Quantum dot scaffolds for metabolic tumor profiling(*) Quantum dot-porphyrin conjugates for two-photon oxygen sensing(*) A nanocrystal-based pH sensor for natural pH ranges