Principal Investigator Rohit Karnik
Nanofluidic devices have unique capabilities for manipulation and sensing of DNA molecules at the single-molecule level. We have developed nanofluidic devices that employ multiple measurements on single molecules to enhance the ability to size DNA molecules. We have also developed a fabrication technique to integrate membranes containing nanopores into microfluidic devices, which decreases noise and enables the design of networks containing nanopores. Combined with active control of molecules, these devices can provide improved DNA analysis and sorting capabilities.