Principal Investigator John Essigmann
Project Website http://jessig.mit.edu/jmegroup/
The Essigmann Lab is in the Department of Chemistry and the Department of Biological Engineering at the Massachusetts Institute of Technology. John is also the Director of the Center for Environmental Health Sciences. The research objective of the lab is to understand the relationship between the structures of lesions formed in the genome by DNA damaging agents and the specific biological endpoints of mutation, cancer, and cell death. The goal of our work on carcinogenesis is to probe the molecular etiology of human cancer. Our parallel studies on antitumor and antiviral drugs focus upon the design of novel compounds that could be useful for the treatment of cancer and infectious diseases.