Center for Systems Biology

We study human biology. Specifically, current research is focused on the imaging and quantitative measurement of cancer treatments. My laboratory employs a variety of techniques including whole body and intravital microscopic imaging, novel chemical approaches for perturbing systems, and innovative sensing strategies including nanotechnology approaches. Our goals are to obtain quantitative and systems-wide global measurements, to perform dynamic serial measurements, and to integrate multiple and various data sets into models. Increasingly, our work has been focused in reconciling the gap that exists between imaging and traditional cell biology research, but in an in vivo setting. Our work on nanomaterials and the development of novel miniaturized next-gen chips has led to advanced clinical trials. While our research is often basic in nature, much of our work has a translational focus, with in vivo imaging playing a major role.