Principal Investigator Allan Myerson
Project Website http://web.mit.edu/myersongroup/index.html
Crystallization is vital to many processes occurring in nature and manufacturing. In chemical, pharmaceutical and food industries, crystallization from solution is widely used for a variety of materials. It is an attractive isolation step during manufacturing as particle formation and purification are combined within a single process. The quality of a crystalline product is usually judged by four main properties: size, purity, morphology, and crystal structure. It is vital in pharmaceutical industry to produce the desired crystal form (polymorph) to assure the bioavailability and stability of the drug substance. Hence it is necessary to control the crystallization process in order to obtain products with desired and reproducible properties.
The Myerson research group focuses on fundamental studies of nucleation, polymorphism, impurity-crystal interactions, novel separation methods, continuous crystallization and industrial applications.
In addition, the Myerson research group actively participates in the Novartis-MIT Center for Continuous Manufacturing.