Entry Date:
August 30, 2011

Online Motif Discovery with WebMOTIFS

Principal Investigator Ernest Fraenkel


WebMOTIFS is an online tool for motif discovery, scoring, analysis, and visualization. It allows you to use different programs to search for DNA-sequence motifs, and to easily combine and evaluate the results.

WebMOTIFS is a combination of two tools, TAMO and THEME. TAMO runs a number of motif discovery programs on input sequences, then combines, analyzes, and clusters the results. TAMO incorporates the motif discovery programs AlignACE, MDscan, MEME, and Weeder. We gratefully acknowledge the authors of these programs. THEME does Bayesian motif analysis, incorporating prior knowledge about likely motifs. The graphic below explained the basic motif discovery and post-processing offered by WebMOTIFS.