Entry Date:
October 22, 2009

Development and Dissemination of Tools for Quantitative Analysis of Biological Data

Principal Investigator Leonid Mirny

Project Website http://knots.mit.edu


These include detection of knots in protein structures (jointly with Prof.Kardar); physical characterization of viruses and their capsids; further development of an algorithm to identify key residues in proteins using evolutionary information; development of web-servers to make these tools widely accessible; biophysical modeling of self-assembly of microtubules and development of the new experimental technique to monitor this process in vivo; and development of new algorithms for analysis of gene expression data.