Entry Date:
October 29, 2008

Optical Control of Signaling Molecules

Principal Investigator Shuguang Zhang

Co-investigator Edward Boyden


Ed Boyden, a member of the MIT media lab and an associate member of McGovern Institute, is a pioneer in the development of optical tools for manipulating electrical activity in neurons. He plans to extend this approach to manipulate intracellular signaling, in collaboration with Shuguang Zhang, director of the MIT Center for Biomedical Engineering and an expert on protein engineering. If successful, this could be a valuable method for determining the function of signaling pathways in vivo and for identifying potential targets for drug development.