Entry Date:
September 26, 2008

Mirny Lab: Architecture and Physics of the Genome

Principal Investigator Leonid Mirny

Project Website http://mirnylab.mit.edu/


What are the physical principles and processes connecting 3D folding to genome function?

The challenge of understanding biological systems from first physical principles is what motivates our research. Biological systems are characterized by remarkable structural complexity at all levels of organization. However, we believe that simple physical models are valuable for describing these systems.

The Laboratory develops multidisciplinary approaches involving:
• Polymer physics theory and simulation
• Statistical interpretation of genome-wide data
• Population genetics and evolutionary theory
• The future of genome architecture is being shaped within our lab

The Mirny Lab fosters a thriving community of talented scientists, providing mentorship and support to researchers at all stages, from secondary school PRIMES students to postdoctoral researchers.