Entry Date:
February 12, 2007

Microarray Monitoring in Chiral Synthesis and Biosynthesis

Principal Investigator Stephen Buchwald

Co-investigator Gregory Stephanopoulos


A major theme in the Flagship project is the microbial, biological or chemical synthesis of chiral chemicals. Within the scope of this theme, as well as the downstream processing of product recovery, methods for the rapid and sensitive monitoring on the chiral products would greatly enhance the overall project goals. In this Inter-University project we will examine a new concept for the monitoring of the chirality of the various products within the goals of the Flagship Research Projects. To this end, microarray technology be explored as the basis for the detection of the amount and product chirality in a high throughput manner.