Entry Date:
January 11, 2007

Standing-Wave Total Internal Reflection Microscopy (SW-TIRM)

Principal Investigator Peter So


Conventional optical microscopy has a resolution about 300 nm, limited by the diffraction of light. We are developing SW-TIRM that may fundamentally overcome the resolution barrier of optical microscopy and achieve resolution below 50 nm. This technique offers the potential to study the dynamics and function of cells and proteins with resolution approaching that of electron microscopes