Entry Date:
December 19, 2006

W.M. Keck Microscope Facility at the Whitehead Institute


The W.M. Keck Microscope Facility provides scientists with the equipment and training necessary to generate and interpret light and electron microscope images. The facility includes state-of-art imaging platforms and image processing and analysis software, including Nikon upright and inverted light microscopes for live cell time-lapse fluorescence, phase contrast, and DIC imaging, Zeiss LSM510 META confocal microscope, Perkin Elmer UltraView RS confocal microscope, Eppendorf microinjection station, Hamamatsu Orca CCD cameras, JEOL 5600LV SEM, Phillips 410 TEM, and microtomes for cutting cryosections for light and electron microscopy. Imaging software packages include OpenLab and Velocity (Improvision), Imaris (BitPlane), and Huygens (SVI).

The facility provides a full-service menu including consulting on imaging projects, sample preparation, imaging, and imaging software. A particular expertise of the facility is immunoelectron microscopy imaging services. The Facility is located on the 4th floor of the Whitehead Institute and is managed by Ms. Nicki Watson. In addition to serving the Whitehead and MIT community, the facility is open to the local research community.