Principal Investigator Alan Oppenheim
Understanding the Information Processing in Biological CellsWe are developing models at different resolutions. High-level models focus on network topology and node interconnectivity, using concepts from random graph theory to examine and analyze the distribution and properties of the signaling network. Low-level models examine the dynamics of cellular signal processing within a new framework that we developed based on interacting Markov chains. We combine these modeling results with experimental data obtained through collaborations with other CSBi investigators to understand how the topologies and dynamics of biological signaling networks influence the properties of the system.