Principal Investigator K Wittrup
Project Website http://web.mit.edu/kdw-lab/
The Wittrup Lab develops protein engineering technology and applies it to the discovery of new biopharmaceuticals. In particular, yeast surface display is used for the directed evolution of protein expression stability, affinity, and specificity. A particular focus is on the development of anti-cancer drugs, with quantitative studies of cellular-level pharmacokinetics and pharmacodynamics.
Research iis predominantly focused on the application of protein engineering to the development of cancer therapeutics.