Entry Date:
January 26, 2006

MIT Biopolymers Laboratory

Principal Investigator Richard F Cook


The Biopolymers Laboratory is a shared instrumentation service laboratory, funded by the Howard Hughes Medical Institute (HHMI) and the MIT Center for Cancer Research with the purpose of providing state of the art research instrumentation to the faculty and staff of MIT.

The concept of the Laboratory is to combine in one location expensive and highly automated instrumentation with the technical expertise needed to operate and maintain it efficiently. The cost of supplies and reagents utilized in a synthesis or analysis is "charged back" to individual research laboratories. As a consequence, each research laboratory has at its disposal hundreds of thousands of dollars worth of sophisticated research equipment and a highly trained technical staff ready to conduct experiment, allowing researchers to utilize modern techniques without having to invest their time, funds and laboratory space on an individual basis.

The Laboratory serves only on-campus laboratories and HHMI researchers.

The concept of the Laboratory is to combine in one location expensive and highly automated instruments with the technical expertise needed to operate and maintain them efficiently. The cost of supplies and reagents utilized in a synthesis or analysis is "charged back" to individual research laboratories. As a consequence, each research laboratory has at its disposal hundreds of thousands of dollars worth of sophisticated research equipment and a highly trained technical staff ready to conduct experiments. The Biopolymers Laboratory allows researchers to utilize modern techniques without having to invest their time, funds and laboratory space on an individual basis.

This facility can assist in: Sequencing of proteins and DNA; Synthesis of oligonucleotides and oligopeptides; Protein micro-sequencing; Electrospray and liquid chromatography mass spectrometry; MALDI TOF mass spectrometry; DNA sequencing; Peptide synthesis and purification; DNA/ RNA synthesis Affymetrix gene chip system RNA expression analysis; Protein digestion - peptide mapping - protein identification; High pressure liquid chromatography; and Intavis (nee ABIMED) peptide arraying on cellulose.