Principal Investigator James Fox
Project Website https://cehs.mit.edu/core-facilities/animal-models/
Project Start Date April 2005
The Animal Models Facilities Core, directed by Professor James Fox of the Division of Comparative Medicine and the Department of Biological Engineering, provides Center members with the latest technology for the application of animal models to environmental health research. Center members are provided with an extensive array of services related to animal models and pathology.
The objective of the Animal Models Facilities Core is to provide Center members with state-of-the-art pathology and imaging support, transgenic resources and a centrally-managed AAALAC-approved animal holding and surgical facility. The Core is staffed with experienced personnel and is equipped with essential equipment to generate genetically engineered mice, cryopreserve sperm and embryos, rederive imported mice by embryo derivation, provide colony management, and prepare and interpret tissue samples by histological and image analysis.
Professor James Fox, the Core director, supervises all operations. He is assisted in this task by, Dr. Suresh Muthupalani (Chief, Comparative Pathologist, DCM), Dr. Vasu Bakthavatchalu (Comparative Pathologist, DCM) Dr. Susan Erdman (Chief of Clinical Services, DCM) and Dr. Alex Garcia (Chief of the Transgenic Mouse Core Facility, DCM). Drs. Suresh Multhupalani and Vasu Bakthavatchalu are experienced board certified veterinary pathologists who consult with Center members in the interpretation of histopathology specimens and other aspects of animal pathology.