Animal Model and Pathology Facilities Core

Animal Model and Pathology Facilities Core

A substantial fraction of the research carried out in the CEHS involves the use of animal models of human disease. To meet this need, the Animal Models and Pathology Facilities Core, directed by Professor James Fox, provides numerous services to Center members, including overseeing husbandry for all the animals used by CEHS members (rats and mice), development of transgenic knock-out and knock-down animal models, histopathology, advanced tissue imaging, DNA sequencing, real-time PCR and other technologies related to cell and molecular biology, as well as the services of board certified pathologists. The Core is comprised of the facilities, services and expertise of the Division of Comparative Medicine at MIT, directed by James Fox.

The goal of this project is to understand how toxic environmental agents perturb biological systems and to determine how such perturbations may affect human health.