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Prof. JoAnne Stubbe
Professor of Chemistry and Biology, Emeritus
Associate Member, Broad Institute
Primary DLC
Department of Chemistry
MIT Room:
18-581
(617) 253-1814
stubbe@mit.edu
https://chemistry.mit.edu/profile/joanne-stubbe/
Areas of Interest and Expertise
Biochemistry and Biophysics
Design of Mechanism-Based Inhibitors for Studying Enzymatic Reaction Mechanisms, as Models for Genetic Diseases and as Potential Antibiotic, Antiparasitic and Anti-Tumor Agents
Mechanisms of Enzyme-Catalyzed Reactions
Mechanisms of Anti-Tumor Antibiotics Degradation of DNA
Bioorganic-Bioinorganic Chemistry
Regulation of the Purine Biosynthetic Pathway
Mechanism of AdoCbl, Manganese, and Tyrosylphenoxy Radical Dependent Reductases
Mechanisms of DNA Cleavers and Bioorganic Cleavers
Polyester Biosynthesis (Biodegradable Polymers)
Organic Chemistry
Biological Chemistry
Recent Work
Projects
July 12, 1999
Department of Chemistry
Polyhydroxybutyrate Polymerase (PHB)
Principal Investigator
JoAnne Stubbe
April 23, 1999
Department of Chemistry
Ribonucleotide Reductases (RNRs): Structure and Function
Principal Investigator
JoAnne Stubbe
Related Faculty
Prof. Christopher C Cummins
Henry Dreyfus Professor of Chemistry
Prof. Rick L Danheiser
Arthur C Cope Professor of Chemistry
Prof. Robert J Gilliard Jr
Novartis Associate Professor of Chemistry