Prof. George B Benedek

Alfred H Caspary Professor of Biological Physics and Physics, Emeritus

Primary DLC

Department of Physics

MIT Room: 4-304

Areas of Interest and Expertise

Self-Association and Phase Transitions in Solutions of Biological and Synthetic Macromolecules
Aggregations and Self-Assembly of Amphiphiles and Proteins in Aqueous Solutions
Molecular Factors that Produce Lens Opacification in Cataracts
Biological and Medical Physics
Biophysics
Experimental Condensed Matter Physics
Critical Phenomena, and Self-Assembly of Micro- and Nano-Structures Constituted of Synthetic or Biological Amphiphiles with Application to the Inhibition of Cataract Disease
Cholesterol Gallstone Formation and Alzheimer's Disease

Research Summary

The research of the Benedek group centers on phase transitions, self-assembly and aggregation of several biological molecules. These phenomena are of biological and medical interest because phase separation, self-assembly and aggregation of biological molecules are known to play a central role in several human diseases such as cataract, Alzheimer's disease, and cholesterol gallstone formation. A combination of experimental work, theoretical analysis, and computer simulations is used to understand the connection between the basic interactions amongst the molecules and the resulting condensed phases.

Recent Work